Hi Maltesh
For question 1, I'm not too sure what you mean by connect to more than one GRC System. You would follow the same steps for the Integration Framework and map your connectors in. The only differences would be in default connector mapping you choose one and you might have MSMP/BRFplus rules that are system specific.
For question 2, you can link to HR or LDAP. You have to maintain the field mappings for the connector to identify the manager field.
I suggest you search this forum as these topics have appeared before.